Imaging the Future: Sustainable MRI Contrast for a Greener World

Novel Solution for future

Knowledgepie Private Limited

Knowledgepie is a cutting-edge biotechnology company that specializes in the development of innovative solutions for medical imaging. With a focus on creating alternative MRI contrast agents, Knowledgepie is revolutionizing the field of medical diagnostics with its groundbreaking technology.

Our flagship product is a nanoparticle-based contrast agent that is developed through a green route, offering numerous advantages over traditional gadolinium-based contrast agents.

 

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mission

At Knowledgepie, our mission is to innovate safer contrast agents for cancer detection and therapy, prioritizing patient safety, enhancing diagnostic precision, and redefining global cancer care through advanced research, ethical practices, and collaboration with healthcare professionals.

vision

To translate ideas and research from bench to hospital, to make an
impact in oncology and to make significant contribution to the global fight against cancer.

 

 

technology

Our developed technology is capped with biocompatible molecules and they form stable aqueous solutions, are non-toxic to normal cells, and show strong cytotoxicity against tumor cells compared to paclitaxel. Synthesis is facile, aqueous, thermo-free, and single-step.

What We Innovate

"XEUJ" As MRI Contrast Agent

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Environment Friendly

It is produced using a green route, which means it is environmentally friendly and has minimal impact on the ecosystem.

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Advantages related to NSF

As an iron-based agent, it carries no risk of nephrogenic systemic fibrosis (NSF) unlike Gd-based contrast agents (GBCAs).

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First 'Make In India Product'

Will be ‘First to market’ ‘Make in India’ product in contrast agent market.

 

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Cost Effective

Our product is cost- effective and having high chemical stability.


Technology

An innovative multifunctional nanoparticle formulation

Contrast agents play a crucial role in imaging applications like MRI by enhancing contrast. Conventional MRI contrast agents are primarily chelates of the rare earth element Gadolinium, which generate positive contrast on T1-weighted images. However, these agents can cause ghosting artifacts, hindering accurate diagnosis. Additionally, concerns regarding their potential toxicity remain unresolved.

The development of our advanced nanoparticle-based contrast agent offers a promising alternative to existing techniques, providing comparable or enhanced functionalities. This system demonstrates potential for simultaneous diagnosis and therapy while addressing the toxicity concerns associated with Gd-based contrast agents

Our nanoparticle solution; MRI Contrast Agent application as T1 CA

Our Team

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Dr. Madhulekha Gogoi

Director & Co-founder

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Mr. Aditya Man Borborah

Co-founder

Ms. Supriya Bora

Business Developer

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Ms. Anusuya Dutta

Project Fellow

Our Investment Partners

Applications

What are the applications of our product?

  • Magnetic Resonance Imaging (MRI) Enhancement: Improves visibility and contrast in MRI scans by altering tissue magnetic properties.
  • Detection and Characterization of Tumors: Crucial for distinguishing tumor tissues from healthy tissue, aiding in diagnosis and treatment planning.
  • Can be used for renal impaired patients also.
  • Theranostics: Researching for targeted therapy and real-time imaging feedback.

MRI Contrast Media

Experience

Join us in the journey

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Years of Research
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